Methyl 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthalene carboxylate (Adapalene Methyl Ester)

CAS No. :

106685-41-0

Molar Mass :

426.55 g/mol

Molecular Formula :

C₂₉H₃₀O₃

Uses :

Methyl 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthalene carboxylate is primarily used as a crucial intermediate in the synthesis of Adapalene, a widely used topical retinoid drug for treating acne, psoriasis, and photoaging, functioning as a key building block that's later hydrolyzed to the final carboxylic acid form. It's also important in research for developing new synthetic routes to Adapalene and studying the effects of its structural components, like the adamantyl group, on biological activity and DNA binding.

Methyl 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthalene carboxylate (Adapalene Methyl Ester)